Investigation of FDG-PET/CT imaging to guide biopsies in the detection of histological transformation of indolent lymphoma.

نویسندگان

  • Caroline Bodet-Milin
  • Françoise Kraeber-Bodéré
  • Philippe Moreau
  • Loïc Campion
  • Benoît Dupas
  • Steven Le Gouill
چکیده

Positron emission tomography using 18F-fluorodeoxyglucose (FDG-PET) has been successfully evaluated in the management of non-Hodgkin's lymphoma (NHL).1-3 Histological transformation (HT) of indolent lymphoma is a dramatic event that occurs in 5-10% of the patients and carries a dismal prognosis.4,5 Previous studies prove that indolent lymphoma entities show a lower FDG uptake when compared with aggressive lymphomas.6-8 We therefore postulated that FDG-PET/CT identifies aggressive transformation sites and can guide biopsies.

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عنوان ژورنال:
  • Haematologica

دوره 93 3  شماره 

صفحات  -

تاریخ انتشار 2008